Objetivos

The main goal of our laboratory is to understand how the glycobiology controls the development, the progression and therapeutics issues in prostate cancer patients. The focus of our projects is based on Immunology and Functional studies and Molecular and Cellular Biology.

IMMUNOTHERAPY FOR CANCER

Immunotherapy is the most promising new cancer treatment approach since the development of the first chemotherapies in the late 1940s. Two main types...

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INTRINSIC ROLES OF GALECTINS IN THE REGULATION OF LYMPHOCYTE ANTI-TUMOR FUNCTIONS

A better understanding of the molecular mechanisms involved in regulating tumor microenvironment is essential in order to develop new therapies which...

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Engineering the tumor microenvironment: hemin conditioning in vivo impairs tumor growth and reprograms angiogenesis and the immune-response in prostate cancer

This project is developed in the context of a national collaboration and aims to get better insights about how Heme-oxygenase-1 (HO-1) modulation in...

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MOLECULAR and CELLULAR BIOLOGY OF THE DISEASE PROGRESSION

Prostate cancer (PCa) is a major problem of health, and it is currently the second most prevalent cancer in men (IARC, WHO). However, its incidence...

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SMALL RNA – ARGONAUTE COMPLEX as REGULATORS OF GLYCOME’S GENES EXPRESSION in PATHOLOGIC CONDITIONS

The recent discovery of the RNA Interference (RNAi) in mammals had a major impact on biomedical research. RNAi requires the presence of small non-coding...

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